Adipocytes Impair Mitoxantrone Cytotoxicity Against Acute Lymphoblastic Leukemia.
Cohen M; Orgel E; Nevarez-Mejia J; Chen T; Neely M; Louie S; Mittelman SD · 2025 · EJHaem
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Introduction Obesity contributes to poorer clinical outcomes in patients with acute lymphoblastic leukemia. We have shown that adipocytes cause anthracycline resistance by absorbing and metabolizing them into less-active alcohol…
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Metadata source: Europe PMC · DOI 10.1002/jha2.70140