Performance of creatinine and cystatin C-based equations to estimate glomerular filtration rate in African children with sickle cell anemia.
Nkoy AB; Mumaka FM; Matoka TT; Ngonde A; Sumaili EK; Bukabau JB; Labarque V; van den Heuvel LP · 2026 · Pediatric nephrology (Berlin, Germany)
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Serum creatinine (SCr), the most used biomarker to evaluate glomerular filtration rate (GFR), might be inaccurate in children with sickle cell anemia (SCA). In this context, cystatin C (SCys) could be of interest. This study…
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Metadata source: Europe PMC · DOI 10.1007/s00467-025-06986-w