e-ISSN: Pending
Replication FailureOpen accessMedicine

Platelet desialylation, apoptosis, and T-lymphocyte-mediated immune dysregulation: unveiling the pathways of platelet clearance in platelet transfusion refractoriness.

Zhou Y; Zhong Z; Mo H; Liang L; Su C; Chen Y; Lu F; Huang Y · 2026 · Research and practice in thrombosis and haemostasis

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

Background Platelet transfusion refractoriness (PTR) is a clinical challenge that can be classified into nonimmunologic and immunologic types, the latter resulting from both platelet alloimmunization and autoimmunity. Recent studies have…

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Metadata source: Europe PMC · DOI 10.1016/j.rpth.2026.103395