Negative / Null Result ReportOpen accessMedicine· cited by 72

Untangling glycaemia and mortality in critical care

Vincent Uyttendaele; Jennifer L. Dickson; Geoffrey M. Shaw; Thomas Desaive; J. Geoffrey Chase · 2017 · Critical Care

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

The finding, in one line

“However, subsequent studies often failed to replicate these results, and they were often unable to achieve consistent, safe control, raising questions about the benefit or harm of GC as well as the nature of the association of glycaemia with mortality and clinical outcomes.”

Abstract

BACKGROUND: Hyperglycaemia is associated with adverse outcomes in the intensive care unit, and initial studies suggested outcome benefits of glycaemic control (GC). However, subsequent studies often failed to replicate these results, and they were often unable to achieve consistent, safe control, raising questions about the benefit or harm of GC as well as the nature of the association of glycaemia with mortality and clinical outcomes. In this study, we evaluated if non-survivors are harder to control than survivors and determined if glycaemic outcome is a function of patient condition and eve

Abstract by Vincent Uyttendaele; Jennifer L. Dickson; Geoffrey M. Shaw; Thomas Desaive; J. Geoffrey Chase, Critical Care (2017) — licensed CC BY 4.0.

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