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Negative / Null Result ReportOpen accessMedicine· cited by 9

The Functional Role of Polyphenols Across the Human Lifespan

Bekir Enes Koca; Sümeyye Sarıtaş; Mikhaël Bechelany; Sercan Karav · 2025 · International Journal of Molecular Sciences

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Polyphenols are bioactive molecules that occur naturally in plants and exhibit a diverse array of properties, including antioxidant, anti-inflammatory, and anti-obesity effects, all of which have been supported by numerous studies. They are categorized into four main groups: flavonoids, phenolic acids, stilbenes, and lignans. Polyphenols demonstrate a wide range of health-promoting effects throughout human life, from the womb to old age. They can exert these effects by modulating signaling pathways, regulating gut microbiota, influencing gene expression, and regulating epigenetic pathways. Thi

Abstract by Bekir Enes Koca; Sümeyye Sarıtaş; Mikhaël Bechelany; Sercan Karav, International Journal of Molecular Sciences (2025) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.3390/ijms262211074