Evaluating the efficacy of G12C inhibitors in conjunction with Gamma Knife radiosurgery for KRAS-mutant non-small cell lung cancer brain metastases.
Andrade A; Mureb M; Karaman N; Liu C; Sabari JK; Veluswamy RR; Bernstein K; Donahue BR · 2026 · Journal of neuro-oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
PURPOSE: KRAS G12C mutations occur in approximately 11% of non-small-cell lung cancer (NSCLC) patients and are associated with aggressive disease and poor prognosis. Although KRAS G12C-inhibitors are now approved, their impact on Gamma…
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Metadata source: Europe PMC · DOI 10.1007/s11060-026-05547-x