Negative / Null Result ReportOpen accessMedicine

Polymorphisms of estrogen metabolism-related genes ESR1 , UGT2B17 , and UGT1A1 are not associated with osteoporosis in artificial menopausal Japanese women

Megumi Yokota; Akira Hirasawa; Kazuya Makita; Tomoko Akahane; Kensuke Sakai; Takeshi Makabe; Yuko Horiba; Wataru Yamagami · 2015 · Menopause Review

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Introduction : Bilateral salpingo-oophorectomy (BSO) is a risk factor for osteoporosis. Previous studies have reported an association between genetic polymorphisms and the risk of developing osteoporosis. However, the relationship between osteoporosis and genetic polymorphisms in Japanese women treated with BSO is not well understood. To improve the quality of life for post-BSO patients, it is important to determine the genetic factors that influence their risk for osteoporosis. The aim of this study was to investigate the association between gene variations of estrogen metabolism-related gene

Abstract by Megumi Yokota; Akira Hirasawa; Kazuya Makita; Tomoko Akahane; Kensuke Sakai; Takeshi Makabe; Yuko Horiba; Wataru Yamagami, Menopause Review (2015) — licensed CC BY 4.0.

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