Culture of skeletal myoblasts from human donors aged over 40 years: dynamics of cell growth and expression of differentiation markers
Cherubino Paolo; Sala Andrea; Casalone Rosario; Bettaccini Alessia A; Baj Andreina; Toniolo Antonio Q · 2005 · Journal of Translational Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Background Local myogenesis, neoangiogenesis and homing of progenitor cells from the bone marrow appear to contribute to repair of the infarcted myocardium. Implantation into heart tissues of autologous skeletal myoblasts has been associated with improved contractile function in animal models and in humans with acute myocardial ischemia. Since heart infarction is most prevalent in individuals of over 40 years of age, we tested whether culture methods available in our laboratory were adequate to obtain sufficient numbers of differentiated skeletal myoblasts from muscle biopsy specimens
Abstract by Cherubino Paolo; Sala Andrea; Casalone Rosario; Bettaccini Alessia A; Baj Andreina; Toniolo Antonio Q, Journal of Translational Medicine (2005) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/1479-5876-3-21