Utility of Polygenic Risk Scores in Families with Exceptional Longevity
Xicota L; Cheng R; Barral S; Honig LS; Schupf N; Gu Y; Andersen S; Cosentino S · 2025 · Preprint
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
ABSTRACT Introduction Polygenic risk scores (PRS) have been used to assess an individual’s risk for various diseases, including Alzheimer’s disease (AD). This study applied the PRS approach to a cohort of families ascertained for healthy…
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Metadata source: Europe PMC · DOI 10.1101/2025.07.21.25331660