YME1L1 is Dispensable for T Lymphocyte Activation Despite its Upregulation and Activity
Malpica G; Joaquim M; Machado RS; Fernandes J; Hall MJ; Martins G; Morais VA; Veldhoen M · 2026 · Preprint
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Mitochondrial dynamics are critical for T cell activation, differentiation, and survival. The inner mitochondrial membrane ATP-dependent metalloprotease YME1L1 regulates proteostasis and the processing of optic atrophy protein 1 (OPA1),…
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Metadata source: Europe PMC · DOI 10.64898/2026.03.16.712079