Interaction of chronic daily headache, dietary intake of iron, and FTO genotype
Yeganeh Shekari; Zahra Mahmoodi; Mohammadtaghi Ghorbani Hesari; Parsa Bahmani; Shailin Abdoli Rezaei; Abdolrahman Parhiz; Masoomeh Alsadat Mirshafaei; Fatemeh Sadat Fahimzad · 2026 · Molecular Pain
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Background: Chronic daily headache (CDH) is known to be a common and debilitating disease that is influenced by genetic, dietary, and lifestyle factors. Iron (Fe) plays a key role in energy metabolism and neurotransmitter synthesis, while the FTO gene polymorphism (rs9939609) may play a role in modulating nutritional responses and nutrient metabolism. This study aimed to determine the interaction between CDH odds, dietary iron intake, and FTO genotype. Methods: This case-control study was conducted on 150 CDH patients and 150 healthy individuals aged 40–80 years. Participants were assessed for
Abstract by Yeganeh Shekari; Zahra Mahmoodi; Mohammadtaghi Ghorbani Hesari; Parsa Bahmani; Shailin Abdoli Rezaei; Abdolrahman Parhiz; Masoomeh Alsadat Mirshafaei; Fatemeh Sadat Fahimzad, Molecular Pain (2026) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1177/17448069261439611