Efficacy and safety of esketamine versus propofol in electroconvulsive therapy for treatment-resistant depression: A randomized, double-blind, controlled, non-inferiority trial.
Zeng QB; Zou DC; Huang XB; Shang DW; Huang X; Yang XH; Ning YP; Balbuena L · 2025 · Journal of affective disorders
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Electroconvulsive therapy (ECT) is a commonly used alternative for treatment-resistant depression (TRD). Although esketamine has a rapid pharmacological antidepressant action, it has not been studied as an ECT anesthetic. The…
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Metadata source: Europe PMC · DOI 10.1016/j.jad.2024.09.038