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Negative / Null Result ReportOpen accessMedicine· cited by 9

Immune dysregulation in endometriosis: the T cell perspective

Danielle J Sisnett; Katherine B Zutautas; Dan Hoang Nguyet Vo; Asha Ravishanker; Jaelis P. Holmes; Alexandra Wodz; Chandrakant Tayade · 2026 · Frontiers in Immunology

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The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Endometriosis is a chronic inflammatory, hormone dependent disorder that affects more than 200 million women worldwide. Immune dysfunction has emerged as one of the predominant mechanisms facilitating endometriosis lesion growth and survival. In particular, T cell subsets are predominant effector immune cells within the complex endometriosis lesion microenvironment. T cell biology encompasses a highly regulated and diverse network of cellular differentiation, antigen recognition, and immune regulation, all of which play critical roles in immune homeostasis. This complexity becomes particularly

Abstract by Danielle J Sisnett; Katherine B Zutautas; Dan Hoang Nguyet Vo; Asha Ravishanker; Jaelis P. Holmes; Alexandra Wodz; Chandrakant Tayade, Frontiers in Immunology (2026) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.3389/fimmu.2026.1712360