First dose target attainment with extended infusion regimens of piperacillin and meropenem.
Beijer G; Swartling M; Nielsen EI; Breuer O; Giske CG; Eliasson E; Petersson J · 2025 · Critical care (London, England)
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Standard dosing regimens of meropenem and piperacillin-tazobactam frequently fail to achieve targeted plasma concentrations in critically ill patients. Extended or continuous regimens are often used to improve target attainment.…
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Metadata source: Europe PMC · DOI 10.1186/s13054-025-05445-0