Intravenous administration of ulinastatin (human urinary trypsin inhibitor) in severe sepsis: a multicenter randomized controlled study
Dilip R. Karnad; Rakesh Bhadade; Pradeep Kumar Verma; Nivedita Moulick; Mradul Kumar Daga; Neelima Chafekar; Shivakumar Iyer · 2014 · Intensive Care Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
PURPOSE: Ulinastatin, a serine protease inhibitor, inhibits several pro-inflammatory proteases and decreases inflammatory cytokine levels and mortality in experimental sepsis. We studied the effect of ulinastatin on 28-day all-cause…
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Metadata source: OpenAlex · DOI 10.1007/s00134-014-3278-8