Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans
Sulggi A. Lee; Joel Mefford; Yong Huang; John S. Witte; Jeffrey N. Martin; David W. Haas; Paul J. McLaren; Taisei Mushiroda · 2016 · AIDS
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
OBJECTIVE: Plasma kynurenine/tryptophan ratio, a biomarker of indoleamine 2,3-dioxygenase-1 (IDO) activity, is a strong independent predictor of mortality in HIV-infected Ugandans initiating antiretroviral therapy (ART) and may play a key…
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Metadata source: OpenAlex · DOI 10.1097/qad.0000000000001124