Systemic Therapies for HER2-Positive Advanced Breast Cancer
Vasileios Angelis; Alicia Okines · 2023 · Cancers
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Despite recent advances, HER2-positive advanced breast cancer (ABC) remains a largely incurable disease, with resistance to conventional anti-HER2 drugs ultimately unavoidable for all but a small minority of patients who achieve an enduring remission and possibly cure. Over the past two decades, significant advances in our understanding of the underlying molecular mechanisms of HER2-driven oncogenesis have translated into pharmaceutical advances, with the developing of increasingly sophisticated therapies directed against HER2. These include novel, more potent selective HER2 tyrosine kinase in
Abstract by Vasileios Angelis; Alicia Okines, Cancers (2023) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3390/cancers16010023