Negative / Null Result ReportOpen accessMedicine· cited by 9

European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) steatotic liver disease special interest group position paper on screening, diagnosis and investigation of paediatric metabolic dysfunction‐associated steatotic liver disease

Jake Peter Mann; Sander Lefere; Maarten Buytaert; Anna Alisi; Cigdem Arikan; Jernej Brecelj; Rachel M. Brown; Irene Degrassi · 2026 · Journal of Pediatric Gastroenterology and Nutrition

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common reason for elevated liver enzymes in children in Europe, affecting more than 5% of all children. Since the last iteration of this position paper, there have been substantial advances in our understanding of the disease. After a detailed literature review and thorough discussion, we established consensus recommendations for the diagnosis and assessment of MASLD in children. Alanine aminotransferase (ALT) ≥ 30 IU/L is a suitable screening test for MASLD in children over 10 years of age with obesity (body mass ind

Abstract by Jake Peter Mann; Sander Lefere; Maarten Buytaert; Anna Alisi; Cigdem Arikan; Jernej Brecelj; Rachel M. Brown; Irene Degrassi, Journal of Pediatric Gastroenterology and Nutrition (2026) — licensed CC BY 4.0.

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