Islatravir Has a High Barrier to Resistance and Exhibits a Differentiated Resistance Profile from Approved Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
Tracy L. Diamond; Winnie Ngo; Min Xu; Shih Lin Goh; Silveria Rodriguez; Ming‐Tain Lai; Ernest Asante‐Appiah; Jay A. Grobler · 2022 · Antimicrobial Agents and Chemotherapy
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Islatravir (ISL) is a nucleoside reverse transcriptase translocation inhibitor (NRTTI) that inhibits human immunodeficiency virus (HIV) reverse transcription by blocking reverse transcriptase (RT) translocation on the primer:template. ISL…
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Metadata source: OpenAlex · DOI 10.1128/aac.00133-22