Final report on North Central Cancer Treatment Group N0877 (alliance): A phase II randomized, placebo-controlled trial of chemoradiotherapy with or without dasatinib for glioblastoma.
Breen WG; Dixon JG; Anderson SK; Sarkaria JN; Brown PD; Yan ES; Kizilbash S; Galanis E · 2025 · Neuro-oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Dasatinib is an oral inhibitor of the Src kinase family, with preclinical data indicating impact on gliomagenesis, tumor invasion, and radiosensitivity. Methods North Central Cancer Treatment Group N0877 is a phase 1 dose…
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Metadata source: Europe PMC · DOI 10.1093/neuonc/noaf156