Efficacy of Carboplatin Alone and in Combination with ABT888 in Intracranial Murine Models of BRCA -Mutated and BRCA –Wild-Type Triple-Negative Breast Cancer
Olga Karginova; Marni B. Siegel; Amanda E.D. Van Swearingen; Allison M. Deal; Bárbara Adamo; Maria J. Sambade; Soha Bazyar; Nana Nikolaishvili‐Feinberg · 2015 · Molecular Cancer Therapeutics
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Patients with breast cancer brain metastases have extremely limited survival and no approved systemic therapeutics. Triple-negative breast cancer (TNBC) commonly metastasizes to the brain and predicts poor prognosis. TNBC frequently…
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Metadata source: OpenAlex · DOI 10.1158/1535-7163.mct-14-0474