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Negative / Null Result ReportOpen accessMedicine

The Effects of Clindamycin and Cefazolin on Osteogenesis of Periodontal Ligament Stem Cells: An In vitro Study

Mohsen Dalband; Mona Isapour; Pantea Nazeman · 2016 · Regeneration, Reconstruction & Restoration

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Introduction: Antibiotics are routinely administered in clinical setting for prevention of infections in surgeries and as a routine supplement to the culture medium. The nobility of the present study was to evaluate the effect of two commonly used antibiotics, clindamycin and cefazolin, in dental treatments, on osteogenic capability of periodontal ligament stem cells (PDLSCs). Materials and Methods: PDLSCs were isolated from periodontal ligament (PDL) of the root section out of four healthy extracted teeth. The cells were incubated in the following medium for 28 days: (1) Osteogenic medium (OM

Abstract by Mohsen Dalband; Mona Isapour; Pantea Nazeman, Regeneration, Reconstruction & Restoration (2016) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.22037/rrr.v1i3.13353