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Abandoned HypothesisMedicine

Rifaximin in cirrhosis: when therapeutic drift meets antimicrobial stewardship.

Jalan R; Patel VC; Shoaie S · 2026 · The lancet. Gastroenterology & hepatology

WASTE classifies this as Abandoned Hypothesis · AI classification, approximate

A hypothesis was tested and not supported — a dead end worth knowing about before you pursue it.

Abstract (excerpt)

This Viewpoint examines the evolving role of rifaximin in cirrhosis, arguing that therapeutic drift has outpaced evidence and antimicrobial stewardship. While rifaximin is effective for secondary prevention of recurrent overt hepatic…

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Metadata source: Europe PMC · DOI 10.1016/s2468-1253(26)00076-2