Mycophenolic acid trough level assessment in patients with lupus nephritis; does it make a difference?
Ahmed E. Abdulgalil; Noha H. Elnagdy; Nehal M. Ramadan; Eman Hamza; Ayman Hammad; Mai S Korkor; Atef Elmougy; Ali Sobh · 2025 · Pediatric Rheumatology Online Journal
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Introduction Mycophenolate Mofetil (MMF) has become one of the cornerstone treatments of lupus nephritis (LN). It is converted into mycophenolic acid (MPA), an active metabolite, that displays high inter- and intra-individual pharmacokinetic variability. However, the routine monitoring of MPA trough level is still debatable. Objectives The present study aims to evaluate the relationship between MPA trough levels and both clinical outcomes and drug-related adverse effects during the maintenance phase of LN in Egyptian patients. Methods We included thirty-five adults and twenty-nine chi
Abstract by Ahmed E. Abdulgalil; Noha H. Elnagdy; Nehal M. Ramadan; Eman Hamza; Ayman Hammad; Mai S Korkor; Atef Elmougy; Ali Sobh, Pediatric Rheumatology Online Journal (2025) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/s12969-025-01074-7