Lack of significant association between serum inflammatory cytokine profiles and the presence of colorectal adenoma
Curtis J. Henry; Rebecca L. Sedjo; Andrii I. Rozhok; Jennifer L. Salstrom; Dennis J. Ahnen; Theodore R. Levin; Ralph B. D’Agostino; Steven M. Haffner · 2015 · BMC Cancer
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Inflammatory cytokines in the colonic microenvironment have been shown to increase with advance colorectal cancer disease state. However, the contribution of inflammatory cytokines to pre-malignant disease, such as the formation of adenomas, is unclear. METHODS: Using the Milliplex® MAP Human Cytokine/ Chemokine Magnetic Bead Panel Immunoassay, serum cytokine and chemokine profiles were assayed among participants without an adenoma (n = 97) and those with an adenoma (n = 97) enrolled in the NCI-funded Insulin Resistance Atherosclerosis Colon Study. The concentrations of interleukin
Abstract by Curtis J. Henry; Rebecca L. Sedjo; Andrii I. Rozhok; Jennifer L. Salstrom; Dennis J. Ahnen; Theodore R. Levin; Ralph B. D’Agostino; Steven M. Haffner, BMC Cancer (2015) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/s12885-015-1115-2