Bias in the Composite Outcomes of Kidney-Cardio Protective Trials in Chronic Kidney Disease: A Meta-Epidemiological Study.
Bellos I; Marinaki S; Benetou V · 2026 · Journal of clinical medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background/Objectives : Composite endpoints are commonly used in chronic kidney disease (CKD) trials to enhance statistical efficiency but may not reflect clinically meaningful outcomes. We assessed agreement between composite endpoints…
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Metadata source: Europe PMC · DOI 10.3390/jcm15124840