e-ISSN: Pending
Negative / Null Result ReportOpen accessMedicine

Circulating levels of sclerostin are associated with cardiovascular mortality.

Cristina Novo-Rodríguez; Beatriz García-Fontana; Juan De Dios Luna-Del Castillo; Francisco Andújar-Vera; Verónica Ávila-Rubio; Cristina García-Fontana; Sonia Morales-Santana; Pedro Rozas-Moreno · 2018 · PLoS ONE

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Cardiovascular diseases are a health problem throughout the world, especially in people with diabetes. The identification of cardiovascular disease biomarkers can improve risk stratification. Sclerostin is a modulator of the Wnt/β-catenin signalling pathway in different tissues, and it has recently been linked to vascular biology. The current study aimed to evaluate the relationship between circulating sclerostin levels and cardiovascular and non-cardiovascular mortality in individuals with and without type 2 diabetes. We followed up a cohort of 130 participants (mean age 56.8 years; 48.5% fem

Abstract by Cristina Novo-Rodríguez; Beatriz García-Fontana; Juan De Dios Luna-Del Castillo; Francisco Andújar-Vera; Verónica Ávila-Rubio; Cristina García-Fontana; Sonia Morales-Santana; Pedro Rozas-Moreno, PLoS ONE (2018) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.1371/journal.pone.0199504