Sinonasal microbiome remains stable during dupilumab therapy in chronic rhinosinusitis: a pilot study.
Hirsch T; Moser U; Wolf A; Andrianakis A · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Purpose This prospective pilot study aimed to evaluate whether dupilumab therapy induces measurable changes in the sinonasal microbiome of patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Methods Eight CRSwNP patients…
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Metadata source: Europe PMC · DOI 10.1007/s00405-026-10378-7