Negative / Null Result ReportOpen accessMedicine· cited by 33

Centromedian Nucleus of the Thalamus Deep Brain Stimulation for Genetic Generalized Epilepsy: A Case Report and Review of Literature

Shruti Agashe; David B. Burkholder; Keith Starnes; Jamie J. Van Gompel; Brian N. Lundstrom; Gregory A. Worrell; Nicholas M. Gregg · 2022 · Frontiers in Human Neuroscience

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

There is a paucity of treatment options for cognitively normal individuals with drug resistant genetic generalized epilepsy (GGE). Centromedian nucleus of the thalamus (CM) deep brain stimulation (DBS) may be a viable treatment for GGE. Here, we present the case of a 27-year-old cognitively normal woman with drug resistant GGE, with childhood onset. Seizure semiology are absence seizures and generalized onset tonic clonic (GTC) seizures. At baseline she had 4-8 GTC seizures per month and weekly absence seizures despite three antiseizure medications and vagus nerve stimulation. A multidisciplin

Abstract by Shruti Agashe; David B. Burkholder; Keith Starnes; Jamie J. Van Gompel; Brian N. Lundstrom; Gregory A. Worrell; Nicholas M. Gregg, Frontiers in Human Neuroscience (2022) — licensed CC BY 4.0.

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