A ratiometric ER calcium sensor for quantitative comparisons across cell types and subcellular regions
Ryan J. Farrell; S. Thomas Hennigan; Kirsten G. Bredvik; Michael B. Hoppa; Timothy A. Brown; Timothy A. Ryan · 2026 · The Journal of General Physiology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
The ER is an important regulator of Ca2+ in cells and dysregulation of ER Ca2+ homeostasis can lead to numerous pathologies. Understanding how various pharmacological and genetic perturbations of ER Ca2+ homeostasis impact cellular…
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Metadata source: OpenAlex · DOI 10.1085/jgp.202413564