ICMT deficiency ameliorates weight loss and mortality, but not tumor formation in a mouse model of liver cancer.
Czarnota P; Gromowski T; Golda A; Bryzek D; Lasota S; Koziel J; Wilamowski M; Cisowski J · 2026 · Cell communication and signaling : CCS
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Liver cancer often arises in the setting of chronic liver disease and remains a major global health challenge with limited effective treatments. Isoprenylcysteine Carboxyl Methyltransferase (ICMT) is an enzyme that catalyzes the…
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Metadata source: Europe PMC · DOI 10.1186/s12964-026-02775-6