A randomized phase II/III study of paclitaxel/carboplatin/metformin versus paclitaxel/carboplatin/placebo as initial therapy for measurable stage III or IVA, stage IVB, or recurrent endometrial cancer: An NRG oncology/GOG study.
Bae-Jump VL; Sill MW; Gehrig PA; Merker JD; Corcoran DL; Pfefferle AD; Hayward MC; Walker JL · 2025 · Gynecologic oncology
WASTE classifies this as Failed Experiment Report · AI classification, approximate
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Abstract (excerpt)
Introduction We evaluated the efficacy of the addition of the anti-diabetic drug metformin to standard-of-care paclitaxel and carboplatin (PC) in patients with advanced and recurrent endometrial cancer (EC). Methods In this phase II/III…
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Metadata source: Europe PMC · DOI 10.1016/j.ygyno.2025.03.003