Negative / Null Result ReportOpen accessMedicine· cited by 15

Thromboelastography With Platelet Mapping is Not an Effective Measure of Platelet Inhibition in Patients With Spontaneous Intracerebral Hemorrhage on Antiplatelet Therapy

Helena Lam; Nakul Katyal; Catherine D. Parker; Prashant Natteru; Premkumar Nattanamai; Christopher R. Newey; Chadd K. Kraus · 2018 · Cureus

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Thromboelastography with platelet mapping (TEG-PM) is a modality to measure platelet function, especially in patients taking antiplatelet medications. It consists of two components: arachidonic acid (AA), which is sensitive to aspirin, and adenosine diphosphate (ADP), which is sensitive to clopidogrel. In patients with spontaneous intracerebral hemorrhages (sICH), the clinical interpretation of platelet mapping is unclear. The objective of this study was to evaluate TEG-PM in patients with sICH on aspirin and/or clopidogrel who receive platelet transfusions. This study was an IRB-approved, ret

Abstract by Helena Lam; Nakul Katyal; Catherine D. Parker; Prashant Natteru; Premkumar Nattanamai; Christopher R. Newey; Chadd K. Kraus, Cureus (2018) — licensed CC BY 4.0.

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