Negative / Null Result ReportOpen accessMedicine· cited by 120

A Natural Product Telomerase Activator Lengthens Telomeres in Humans: A Randomized, Double Blind, and Placebo Controlled Study

Laura Salvador; Gunasekaran Singaravelu; Calvin B. Harley; Peter L. Flom; Anitha Suram; Joseph M. Raffaele · 2016 · Rejuvenation Research

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

TA-65 is a dietary supplement based on an improved formulation of a small molecule telomerase activator that was discovered in a systematic screening of natural product extracts from traditional Chinese medicines. This study summarizes the findings on telomere length (TL) changes from a randomized, double blind, placebo controlled study of TA-65 over a 1 year period. The study was conducted on 117 relatively healthy cytomegalovirus-positive subjects aged 53-87 years old. Subjects taking the low dose of TA-65 (250 U) significantly increased TL over the 12 months period (530 ± 180 bp; p = 0.005)

Abstract by Laura Salvador; Gunasekaran Singaravelu; Calvin B. Harley; Peter L. Flom; Anitha Suram; Joseph M. Raffaele, Rejuvenation Research (2016) — licensed CC BY 4.0.

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