DOES HIPEC IMPROVE OUTCOMES IN GASTRIC CANCER PATIENTS TREATED WITH PERIOPERATIVE CHEMOTHERAPY AND RADICAL SURGERY? A PROPENSITY-SCORE MATCHED ANALYSIS
Thiago Pereira Diniz; Wilson Luiz da Costa; Victor Hugo Fonseca de Jesus; Héber S. C. Ribeiro; Alessandro Landskron Diniz; André Luís de Godoy; Igor Correia de Farias; Sílvio Melo Torres · 2019 · Journal of Surgical Oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Hyperthermic intraperitoneal chemotherapy (HIPEC) has been associated with improved survival when compared with surgery alone for non-metastatic gastric cancer patients in randomized trials and meta-analyses. However, little evidence is available regarding the use of HIPEC in nonmetastatic patients who are treated with perioperative chemotherapy and radical surgery. The aim of this study was to investigate the putative survival benefit of HIPEC in the subgroup of gastric cancer patients treated with perioperative chemotherapy and surgery. PATIENTS AND METHODS: This was a retrospect
Abstract by Thiago Pereira Diniz; Wilson Luiz da Costa; Victor Hugo Fonseca de Jesus; Héber S. C. Ribeiro; Alessandro Landskron Diniz; André Luís de Godoy; Igor Correia de Farias; Sílvio Melo Torres, Journal of Surgical Oncology (2019) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke
Negative / Null Result ReportDuodenal Infusion of Donor Feces for Recurrent Clostridium difficile
Negative / Null Result ReportStenting versus Endarterectomy for Treatment of Carotid-Artery Stenosis
Negative / Null Result ReportEffects of Combination Lipid Therapy in Type 2 Diabetes Mellitus
Replication FailureA Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma
Negative / Null Result ReportSpironolactone for Heart Failure with Preserved Ejection Fraction
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: OpenAlex · DOI 10.1002/jso.25823
