Is Ankyrin a genetic risk factor for psychiatric phenotypes?
Alejandro Gella; Mònica Segura; Núria Durany; Bruno Pfuhlmann; Gerald Stöber; Micha Gawlik · 2011 · BMC Psychiatry
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Genome wide association studies reported two single nucleotide polymorphisms in ANK3 (rs9804190 and rs10994336) as independent genetic risk factors for bipolar disorder. Another SNP in ANK3 (rs10761482) was associated with schizophrenia in a large European sample. Within the debate on common susceptibility genes for schizophrenia and bipolar disorder, we tried to investigate common findings by analyzing association of ANK3 with schizophrenia, bipolar disorder and unipolar depression. METHODS: We genotyped three single nucleotide polymorphisms (SNPs) in ANK3 (rs9804190, rs10994336,
Abstract by Alejandro Gella; Mònica Segura; Núria Durany; Bruno Pfuhlmann; Gerald Stöber; Micha Gawlik, BMC Psychiatry (2011) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
Reproducible brain-wide association studies require thousands of individuals
Negative / Null Result ReportDaily Left Prefrontal Transcranial Magnetic Stimulation Therapy for Major Depressive Disorder
Negative / Null Result ReportEarly Brain Overgrowth in Autism Associated With an Increase in Cortical Surface Area Before Age 2 Years
Negative / Null Result ReportObjective evaluation of anosmia and ageusia in COVID‐19 patients: Single‐center experience on 72 cases
Negative / Null Result ReportPolarity and timing-dependent effects of transcranial direct current stimulation in explicit motor learning
Negative / Null Result ReportThe feedback-related negativity (FRN) revisited: New insights into the localization, meaning and network organization
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: OpenAlex · DOI 10.1186/1471-244x-11-103