Exome sequencing early in outpatient evaluation in NCGENES 2: Changing the course of the diagnostic odyssey?
Roman TS; Gray SM; Sneddon TP; Foreman AKM; Lee K; Powell CM; Weck KE; Berg JS · 2026 · HGG advances
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
The impact of clinical exome and genome sequencing (ES/GS) depends on the clinical setting. In the sequencing arm of a multifactor randomized clinical trial to evaluate broadening access, we assessed the diagnostic and inconclusive…
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Metadata source: Europe PMC · DOI 10.1016/j.xhgg.2026.100605