Therapeutic Potential of Short-Chain Fatty Acids in Gastrointestinal Diseases
Mengting Zhu; Jonathan Lee · 2025 · Nutraceuticals
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Short-chain fatty acids (SCFAs) are metabolites derived from the fermentation of dietary fibre by gut bacteria. SCFAs function as essential regulators of host-microbiome interactions by participating in numerous physiological and pathological processes within the gastrointestinal (GI) tract. In recent years, the depletion of SCFAs has been increasingly linked to the pathogenesis of GI diseases. In this review, we summarize the current understanding of the therapeutic mechanisms of SCFAs in GI diseases, including inflammatory bowel disease, irritable bowel syndrome, metabolic dysfunction-associ
Abstract by Mengting Zhu; Jonathan Lee, Nutraceuticals (2025) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3390/nutraceuticals5030019