Single nucleotide polymorphism rs6716901 in SLC25A12 gene is associated with Asperger syndrome
Jaroslava Durdiaková; Varun Warrier; Simon Baron‐Cohen; Bhismadev Chakrabarti · 2014 · Molecular Autism
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Autism Spectrum Conditions (ASC) are a group of developmental conditions which affect communication, social interactions and behaviour. Mitochondrial oxidative dysfunction has been suggested as a mechanism of autism based on the results of multiple genetic association and expression studies. SLC25A12 is a gene encoding a calcium-binding carrier protein that localizes to the mitochondria and is involved in the exchange of aspartate for glutamate in the inner membrane of the mitochondria regulating the cytosolic redox state. rs2056202 SNP in this gene has previously been associated w
Abstract by Jaroslava Durdiaková; Varun Warrier; Simon Baron‐Cohen; Bhismadev Chakrabarti, Molecular Autism (2014) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/2040-2392-5-25