Emergency Department–Initiated Buprenorphine for Opioid Use Disorder
Gail D’Onofrio; Andrew A. Herring; Kathryn F. Hawk; Jeanmarie Perrone; Ethan A. Cowan; Ryan P. McCormack; James D Dziura; Abigail G. Matthews · 2026 · JAMA
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
Importance: Extended-release injectable buprenorphine may expand the reach of initiating medications for opioid use disorder in high-risk and hard-to-reach individuals who visit the emergency department (ED) and can be administered in low…
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WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: OpenAlex · DOI 10.1001/jama.2025.27019