Evaluating the Efficacy of Propofol Against Isoniazid-Induced Seizures: A Comparative Study with Diazepam and Pyridoxine in Swiss Albino Mice
Sohal P; Gupta K; Kaushal S; Mullins ME · 2025 · Preprint
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
ABSTRACT Objective Acute isoniazid toxicity causes refractory seizures due to pyridoxine deficiency-mediated gamma-aminobutyric acid depletion. While pyridoxine is the established antidote, its limited availability in emergency settings…
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Metadata source: Europe PMC · DOI 10.1101/2025.09.17.676905