Elraglusib, a Glycogen Synthase Kinase 3β Inhibitor, plus Chemotherapy with or without Immunotherapy in Patients with Recurrent, Metastatic Salivary Gland Carcinoma.
Hanna GJ; Scarfo N; Shin KY; O'Neill A; Bedard V; Dennis MJ; Sehgal K; Jo VY · 2026 · Clinical cancer research : an official journal of the American Association for Cancer Research
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Purpose Glycogen synthase kinase 3β (GSK-3β) is a known therapeutic target in cancer. Aberrant nuclear GSK-3β (nGSK-3β) expression has been shown in some salivary gland cancers. Elraglusib is a small-molecule GSK-3β inhibitor with…
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Metadata source: Europe PMC · DOI 10.1158/1078-0432.ccr-25-2731