Mapping the ABC transporter landscape in the human lung: A comprehensive characterisation of P-gp, MRP1 and BCRP expression and functional activity in human lung epithelial cells.
Simon S; Shanmugalingam T; Neu T; Schneider-Daum N; Cantrill C; Lehr CM · 2025 · European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Active efflux transporters can play a substantial role in the drug disposition of their substrates in the human body. Efflux transporters like P-glycoprotein (P-gp), multidrug resistance associated protein 1 (MRP1) and breast cancer…
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Metadata source: Europe PMC · DOI 10.1016/j.ejps.2025.107333