Vaccines targeting the primary amino acid sequence and conformational epitope of amyloid‐β had distinct effects on neuropathology and cognitive deficits in EAE/AD mice
Xiaolin Yu; Jie Zhu; Xiang‐meng Liu; Peng‐xin Xu; Yue Zhang; Rui‐tian Liu · 2020 · British Journal of Pharmacology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
BACKGROUND AND PURPOSE: Immunotherapeutic intervention is one of the most promising strategies for the prevention and treatment of Alzheimer's disease (AD). Although they showed great success in AD mouse models, the clinical trials of many…
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Metadata source: OpenAlex · DOI 10.1111/bph.15015