Prediction of Anthracycline Benefit in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Early-Stage Breast Cancer by the MammaPrint 70-Gene Signature for Patients Enrolled in the FLEX Study.
O'Shaughnessy J; Brufsky AM; Layeequr Rahman R; Osborne CR; Mahtani R; Elkhanany A; Graham CL; Brown E · 2026 · JCO precision oncology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Purpose Randomized trials have not demonstrated clear benefit from anthracyclines for patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative (HER2-) early breast cancer (EBC). The MammaPrint 70-gene…
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Metadata source: Europe PMC · DOI 10.1200/po-25-01285