Effects of reducing sedentary behaviour on heart rate variability and cardio-metabolic biomarkers in desk workers with untreated high blood pressure.
Alansare AB; Muldoon MF; Perera S; Huber KA; Conroy MB; Jakicic JM; Gibbs BB · 2026 · Experimental physiology
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
Lower sedentary behaviour (SB) has been associated with reduced cardiovascular disease and mortality. Yet, few trials have evaluated cardiovascular mechanisms of benefit. We examined the effects of a SB reduction intervention on heart rate…
Excerpt shown for reference under fair use — read the full paper at the publisher.
Hosted by the publisher — may require access.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke
Negative / Null Result ReportDuodenal Infusion of Donor Feces for Recurrent Clostridium difficile
Negative / Null Result ReportStenting versus Endarterectomy for Treatment of Carotid-Artery Stenosis
Negative / Null Result ReportEffects of Combination Lipid Therapy in Type 2 Diabetes Mellitus
Replication FailureA Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma
Negative / Null Result ReportSpironolactone for Heart Failure with Preserved Ejection Fraction
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: Europe PMC · DOI 10.1113/ep093468