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Negative / Null Result ReportOpen accessMedicine· cited by 26

Progressive multiple sclerosis: Evaluating current therapies and exploring future treatment strategies

Marelisa Albelo-Martínez; Syed Rizvi · 2025 · Neurotherapeutics

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Progressive forms of multiple sclerosis (MS) include primary progressive MS (PPMS) and secondary progressive MS (SPMS). Unlike relapsing-remitting MS (RRMS), progressive MS is recognized by relentless progression with accumulating disability, rare to no relapses nor new activity on MRIs. Clinically, neurologic worsening in MS can occur in the relapsing-remitting (RRMS) phase of disease due to incomplete recovery from neuroinflammatory relapses. However, a progressive disease course is the dominant factor related to accumulating disability. There is persistent central nervous system (CNS) compa

Abstract by Marelisa Albelo-Martínez; Syed Rizvi, Neurotherapeutics (2025) — licensed CC BY 4.0.

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Metadata source: OpenAlex · DOI 10.1016/j.neurot.2025.e00601