Acute overfeeding impairs meal-stimulated adipose tissue microvascular blood flow in healthy adults independent of changes in adiposity.
Brayner B; Mason S; Karimi E; Keske MA; Roberts-Thomson KM; Parker L; Betik AC; Thomas HJ · 2026 · American journal of physiology. Endocrinology and metabolism
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
Subcutaneous adipose tissue microvascular blood flow (MBF) increases in response to insulin or a meal, with gastric inhibitory polypeptide (GIP) being a proposed mechanism. This vascular response is blunted in people with insulin…
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Metadata source: Europe PMC · DOI 10.1152/ajpendo.00028.2026