GABA<sub>B</sub> receptor-mediated modulation of sensory neuron excitability: Roles of Ca<sub>V</sub>2.2, G-protein-coupled inwardly rectifying potassium (GIRK) channels, and hyperpolarisation-activated cyclic nucleotide-gated (HCN) channels in human and mouse nociception.
Brizuela M; Bony AR; Garcia-Caraballo S; Adams DJ; Brierley SM · 2026 · Experimental physiology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage-gated calcium and potassium channels by G protein-coupled receptors plays a key role in dampening nociceptive transmission. Both baclofen and the…
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Metadata source: Europe PMC · DOI 10.1113/ep093318