Impacts of methionine oxidation on product quality and anti-tumor activity of a therapeutic monoclonal antibody.
Sun Q; Miao Z; Bian L; Teng F; Guo H; Lin XA; Zhang X; Zhang F · 2026 · Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Methionine oxidation in monoclonal antibodies (mAbs) could critically compromise drug stability and efficacy. This investigation comprehensively evaluated the structural and functional impacts of oxidation on a mAb An under long-term…
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Metadata source: Europe PMC · DOI 10.1016/j.jchromb.2026.124920